{"id":7,"date":"2018-11-16T16:13:42","date_gmt":"2018-11-16T21:13:42","guid":{"rendered":"http:\/\/orgmedchem.nipissingu.ca\/?page_id=7"},"modified":"2026-07-15T09:40:20","modified_gmt":"2026-07-15T13:40:20","slug":"publications","status":"publish","type":"page","link":"https:\/\/wpms.nipissingu.ca\/orgmedchem\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"

Student Trainees are underlined<\/em><\/p>\n

Mukund Jha,* Amitabh Jha. From Spice to Scaffold: Design and Development of Curcumin Analogs to Combat Pancreatic Cancer. Organics<\/em>, 2026<\/strong>, 7<\/em>, 30. \"PDF\"<\/a><\/p>\n

Mukund Jha,* Dani Youssef, Haley Sheehy, Amitabh Jha. Synthesis and pharmacology of clinical drugs containing isoindoline heterocycle core. Organics<\/em>, 2025<\/strong>, 6<\/em>, 3. \"PDF\"<\/a><\/p>\n

\"\"<\/p>\n

Our article has been highlighted as the cover story<\/p>\n<\/div>\n

Organics-Editor\u2019s Choice Article Certificate<\/a><\/p>\n

Ryoga Hojo<\/span>, Spencer Short<\/span>, Mukund Jha.* Synthesis of 1,2-fused tricyclic indoles via Cu-\/base-mediated hydroamination of alkynes. The<\/em>\u00a0Journal of Organic Chemistry<\/em>, 2019<\/strong>, 84, 16095-16104. \"PDF\"<\/a><\/p>\n

Spencer Short<\/span>, Steven Rhodes<\/span>, Vishakha S. Bhave, Ryoga Hojo<\/span>, Mukund Jha.* Metal-free hydroamination of alkynes: A mild and concise synthesis of thiazole[3,2-a<\/em>]indoles. Synthesis<\/em>, 2019<\/strong>, 51, 4263-4270. \"PDF\"<\/a><\/p>\n

Steven Rhodes<\/span>, Spencer Short<\/span>, Sidhika Sharma, Ramneet Kaur, Mukund Jha.* One-pot mild and efficient synthesis of [1,3]thiazino[3,2-a<\/em>]indol-4-ones and their anti-proliferative activity. Organic & Biomolecular Chemistry<\/em>, 2019<\/strong>, 17, 3914-3920. \"PDF\"<\/a><\/p>\n

Shiv Dhiman<\/span>, Nitesh K. Nandwana, Hitesh K. Saini, Dalip Kumar, Krishnan Rangan, Katherine Robertson, Mukund Jha, Anil Kumar. Nickel-catalyzed tandem Knoevenagel condensation and intramolecular direct arylation: Synthesis of pyrazolo[5,1-a]isoquinoline derivatives. Advanced Synthesis & Catalysis<\/em>, 2018<\/strong>, 360, 1973-1983. \"PDF\"<\/a><\/p>\n

Shiv Dhiman<\/span>, Steven Rhodes<\/span>, Dalip Kumar, Anil Kumar, Mukund Jha.* Copper-catalyzed tandem imine formation, Shonogashira coupling and intramolecular hydroamination: A facile synthesis of 3-aryl-\u03b3-carbolines. ChemistrySelect<\/em>, 2017<\/strong>, 2, 8922-8926.\u00a0\"PDF\"<\/a><\/p>\n

Mukund Jha,* Shiv Dhiman<\/span>, T. Stanley Cameron, Dalip Kumar, Anil Kumar. Au-Catalyzed synthesis of thiopyrano[2,3-b]indoles featuring tandem rearrangement and hydroarylation. Organic Letters<\/em>, 2017<\/strong>, 19, 2038-204.\u00a0\"PDF\"<\/a><\/p>\n

Mahesh Akula, P. Yogeeswari, D. Sriram, Mukund Jha, Anupam Bhattacharya. Synthesis and anti-tubercular activity of fused thieno-\/furo-quinoline compounds. RSC Advances<\/em>, 2016<\/strong>, 6, 46073-46080.\u00a0\"PDF\"<\/a><\/p>\n

Ganesh M. Shelke<\/span>, Mukund Jha,* Anil Kumar. Synthesis of indole-annulated sulfur heterocycles using copper catalyzed C-N coupling and palladium-catalyzed direct arylation. Organic & Biomolecular Chemistry<\/em>, 2016<\/strong>, 14, 3450-3458.\u00a0\"PDF\"<\/a><\/p>\n

Yadagiri Thigulla, Mahesh Akula, Prakruti Trivedi, Balram Ghosh, Mukund Jha, Anupam Bhattacharya. Synthesis and anti-cancer activity of 1,4-disubstituted imidazo[4,5-c]quinolines. Organic & Biomolecular Chemistry<\/em>, 2016<\/strong>, 14, 876-883.\u00a0\"PDF\"<\/a><\/p>\n

V. Kameshmysore Rao, Ganesh M. Shelke<\/span>, Ashley Ryan<\/span>, Mukund Jha, Anil Kumar. Iodine-mediated microwave assisted synthesis of 2-arylnaphthofurans via cyclization of 1-(1\u2019-arylvinyl)-2-naphthols. Synthesis<\/em>, 2015<\/strong>, 47, 3990-3996.\u00a0\"PDF\"<\/a><\/p>\n

Mukund Jha,* Ganesh M. Shelke<\/span>, T. Stanley Cameron, Anil Kumar. Access to substituted dihydrothiopyrano[2,3-b]indoles via sequential rearrangements during S-alkylation and Au-catalyzed hydroarylation on indoline-2-thiones. The\u00a0Journal of Organic Chemistry<\/em>, 2015<\/strong>, 80, 5272-5270.\u00a0\"PDF\"<\/a><\/p>\n

Mahesh Akula, Yadagiri Thigulla, Connor Davis<\/span>, Mukund Jha, Anupam Bhattacharya. Synthesis of 4-substituted oxazole[4,5-c]quinolines by direct reaction at C-4 position of oxazoles. Organic & Biomolecular Chemistry<\/em>, 2015<\/strong>, 13, 2600-2605.\u00a0\"PDF\"<\/a><\/p>\n

Ganesh M. Shelke<\/span>, V. Kameshmysore Rao, Mukund Jha, T. Stanley Cameron, Anil Kumar. Microwave assisted catalyst-free synthesis of substituted 1,2,4-triazoles. Synlett<\/em>, 2015<\/strong>, 26, 404-407.\u00a0\"PDF\"<\/a><\/p>\n

Mukund Jha,* Connor Davis<\/span>, Julia Fazzari<\/span>, Mario Vitali<\/span>. BF3 Etherate-mediated microwave-assisted synthesis of thiopyrano[2,3-b]-2-ones. Tetrahedron Letters<\/em>, 2014<\/strong>, 55, 7043-7046.\u00a0\"PDF\"<\/a><\/p>\n

Mukund Jha,* Michael Edmunds<\/span>, Kate-Lyn Lund<\/span>, Ashley Ryan<\/span>. A new route to the versatile synthesis of 5H-thiopyrano[2,3-b:6,5-b\u2019]diindoles via 2-(alkylthio)-indole-3-carbaldehydes. Tetrahedron Letters<\/em>, 2014<\/strong>, 55, 5691-5694.\u00a0\"PDF\"<\/a><\/p>\n

Mukund Jha,* Ganesh M. Shelke<\/span>, Kasiviswanadharaju Pericherla, Anil Kumar. Microwave assisted copper triflate-catalyzed rapid hydration of aryl acetylenes. Tetrahedron Letters<\/em>, 2014<\/strong>, 55, 4814-4816.\u00a0\"PDF\"<\/a><\/p>\n

Mukund Jha,* Ganesh M. Shelke<\/span>, Anil Kumar. Catalyst-free one-pot tandem reduction of oxo- and ene-\/yne- functionalities by hydrazine: Synthesis of substituted oxindoles from isatins. European Journal of Organic Chemistry<\/em>, 2014<\/strong>, 3334-3336.\u00a0\"PDF\"<\/a><\/p>\n

Manoj K. Muthyala, S Choudhary, Khima Pandey, Ganesh M. Shelke<\/span>, Mukund Jha, Anil Kumar. Synthesis of ionic liquid-supported diaryliodonium salts. European Journal of Organic Chemistry<\/em>, 2014<\/strong>, 2365-2370.\u00a0\"PDF\"<\/a><\/p>\n

Darian Blanchard<\/span>, T. Stanley Cameron, Mukund Jha*. Bronstead acid-catalyzed rapid enol-ether formation of 2-hydroxyindole-3-carboxaldehydes. Molecular Diversity<\/em>, 2013<\/strong>, 17, 827-834.\u00a0\"PDF\"<\/a><\/p>\n

Mukund Jha*, Stephanie Guy<\/span>, Ting-Yi Chou<\/span>. Microwave assisted synthesis of indole-annulated dihydropyrano[3,4-c]chromene derivatives via hetero-Diels-Alder reaction. Tetrahedron Letters<\/em>, 2011<\/strong>, 52, 4337-4341.\u00a0\"PDF\"<\/a><\/p>\n

Mukund Jha*, Oro Enaohwo<\/span>, Stephanie Guy<\/span>. Yttrium triflate-catalyzed efficient chemoselective S-benzylation of indoline-2-thiones using benzyl alcohols. Tetrahedron Letters<\/em>, 2011<\/strong>,\u00a052, 684-687.\u00a0\"PDF\"<\/a><\/p>\n

Mukund Jha*, Ting-Yi Chou<\/span>, Brian Blunt<\/span>. General synthesis of mono-, di-, and tri-acetylated indoles from indolin-2-ones. Tetrahedron<\/em>, 2011<\/strong>, 67, 982-989.\u00a0\"PDF\"<\/a><\/p>\n

Mukund Jha*, Oro Enaohwo<\/span>, Ashley Marcellus. Chemoselective S-benzylation of indoline-2-thiones using benzyl alcohols. Tetrahedron Letters<\/em>, 2009<\/strong>, 50, 7184-7187.\u00a0\"PDF\"<\/a><\/p>\n

Mukund Jha*, Brian Blunt<\/span>. Highly efficient one-pot C-, N-, O- acylation of indolin-2-one analogs. Tetrahedron Letters<\/em>, 2009<\/strong>, 50, 6044-6047.\u00a0\"PDF\"<\/a><\/p>\n

Susheel J. Nara, Mukund Jha, Johan Brinkhorst, Tony J. Zemneck, Derek A. Pratt. A simple Cu-catalyzed coupling approach to substituted 3-pyridinols and 5-pyrimidinols. Journal of Organic Chemistry<\/em>, 2008<\/strong>, 73, 9326-9333.\u00a0\"PDF\"<\/a><\/p>\n

M. Soledade C. Pedras, Zoran Minic, Mukund Jha. Purification, functional characterization and inhibition of Brassinin Oxidase, a fungal detoxifying enzyme to overcome plant defenses. FEBS Journal<\/em>, 2008<\/strong>, 275, 3691-3705.\u00a0\"PDF\"<\/a><\/p>\n

Mukund Jha, Derek A. Pratt. Kinetic solvent effects on peroxyl radical reactions. Chemical Communications<\/em>, 2008<\/strong>, 1252-1254.\u00a0\"PDF\"<\/a><\/p>\n

M. Soledade C. Pedras, Mukund Jha, Zoran Minic, Oladapo G. Okeola. Isosteric probes provide structural requirements for detoxification of the phytoalexin brassinin by the fungal pathogen Leptosphaeria maculans. Bioorganic and Medicinal Chemistry<\/em>, 2007<\/strong>, 15, 6054-6061.\u00a0\"PDF\"<\/a><\/p>\n

M. Soledade C. Pedras, Ravi S. Gadagi, Mukund Jha, Vijay K. S. Mamillapalle. Detoxification of the phytoalexin brassinin by isolates of Leptosphaeria maculans involves an inducible hydrolase. Phytochemistry<\/em>, 2007<\/strong>, 68, 1572-1578.\u00a0\"PDF\"<\/a><\/p>\n

M. Soledade C. Pedras, Adewale M. Adio, Mojmir Suchy, Denis P. O. Okinyo, Qing-An Zheng, Mukund Jha, Mohammed G. Sarwar. Detection, characterization and identification of crucifer phytoalexins using high-performance liquid chromatography diode array and electrospray ionization tandem mass spectrometry analyses. Journal of Chromatography A<\/em>, 2006<\/strong>, 1133, 171-183.\u00a0\"PDF\"<\/a><\/p>\n

Oladapo G. Okeola; Mukund Jha; M. Soledade C. Pedras*. Isolation of brassinin oxidase from phytopathogenic fungus Leptosphaeria maculans. Canadian Journal of Plant Pathology<\/em>, 2006<\/strong>, 28, 334.\u00a0\"PDF\"<\/a><\/p>\n

M. Soledade C. Pedras, Mukund Jha. Towards the control of Leptosphaeria maculans: design, synthesis, biological activity and metabolism of potential inhibitors of detoxification of the crucifer phytoalexin brassinin. Bioorganic and Medicinal Chemistry<\/em>, 2006<\/strong>, 14, 4958-4979.\u00a0\"PDF\"<\/a><\/p>\n

M. Soledade C. Pedras, Mukund Jha, Oladapo G. Okeola. Camalexin induces detoxification of the phytoalexin brassinin in the plant pathogen Leptosphaeria maculans. Phytochemistry<\/em>, 2005<\/strong>, 66, 2609-2616.\u00a0\"PDF\"<\/a><\/p>\n

Mukund Jha, M. Soledade C. Pedras, Effect of camalexin and spirobrassinin on the rate of detoxification of the phytoalexin brassinin by L. maculans. Canadian Journal of Plant Pathology,<\/em> 2005<\/strong>, 27, 167.\u00a0\"PDF\"<\/a><\/p>\n

M. Soledade C. Pedras, Mukund Jha. Concise syntheses of the cruciferous phytoalexins brassilexin, sinalexin, wasalexins and analogs: Expanding the scope of the Vilsmeier formylation. Journal of Organic Chemistry<\/em>, 2005<\/strong>, 70, 1828-1834.\u00a0\"PDF\"<\/a><\/p>\n

M. Soledade C. Pedras, Mukund Jha, Pearson W. K. Ahiahonu. The synthesis and biosynthesis of phytoalexins produced by cruciferous plants. Current Organic Chemistry<\/em>, 2003<\/strong>, 7, 1635-1647.<\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

Student Trainees are underlined Mukund Jha,* Amitabh Jha. From Spice to Scaffold: Design and Development of Curcumin Analogs to Combat Pancreatic Cancer. Organics, 2026, 7, 30. Mukund Jha,* Dani Youssef, Haley Sheehy, Amitabh Jha. Synthesis and pharmacology of clinical drugs containing isoindoline heterocycle core. Organics, 2025, 6, 3. Organics-Editor\u2019s Choice Article Certificate Ryoga Hojo, Spencer Read More …<\/a><\/p>\n","protected":false},"author":654,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"open","template":"","meta":{"footnotes":""},"class_list":["post-7","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/wpms.nipissingu.ca\/orgmedchem\/wp-json\/wp\/v2\/pages\/7","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wpms.nipissingu.ca\/orgmedchem\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/wpms.nipissingu.ca\/orgmedchem\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/wpms.nipissingu.ca\/orgmedchem\/wp-json\/wp\/v2\/users\/654"}],"replies":[{"embeddable":true,"href":"https:\/\/wpms.nipissingu.ca\/orgmedchem\/wp-json\/wp\/v2\/comments?post=7"}],"version-history":[{"count":39,"href":"https:\/\/wpms.nipissingu.ca\/orgmedchem\/wp-json\/wp\/v2\/pages\/7\/revisions"}],"predecessor-version":[{"id":299,"href":"https:\/\/wpms.nipissingu.ca\/orgmedchem\/wp-json\/wp\/v2\/pages\/7\/revisions\/299"}],"wp:attachment":[{"href":"https:\/\/wpms.nipissingu.ca\/orgmedchem\/wp-json\/wp\/v2\/media?parent=7"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}